Virotherapy as Potential Adjunct Therapy for Graft-Vs-Host Disease
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چکیده
منابع مشابه
Imatinib as a potential treatment for sclerodermatous chronic graft-vs-host disease.
Juan A. Moreno-Romero, MD; Francesc Fernández-Avilés, MD; Enric Carreras, MD; Montserrat Rovira, MD; Carmen Martı́nez, MD; José M. Mascaró Jr, MD; Department of Dermatology (Drs Moreno-Romero and Mascaró) and Bone Marrow Transplant Unit, Department of Hematology (Drs Fernández-Avilés, Carreras, Rovira, and Martı́nez), Hospital Clı́nic, University of Barcelona, and Department of Dermatology, Hospit...
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AIM To assess the toxicity, tolerance, steroid-sparing capacity, effectiveness, and response rate to imatinib and dasatinib for the treatment of severe sclerotic chronic graft-vs-host disease (scGVHD). METHODS This retrospective study analyzed 8 consecutive patients with severe refractory scGVHD who received salvage therapy with imatinib. Patients intolerant and/or refractory to imatinib rece...
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Thalidomide has been reported to be an effective agent for treatment of chronic graft-versus-host disease (CGVHD). To determine the efficacy of this agent in patients with refractory CGVHD a total of 80 patients who failed to respond to prednisone (PSE) or PSE and cyclosporine (CSA) were treated with thalidomide. Sixteen patients (20%) had a sustained response, 9 with a complete remission and 7...
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BACKGROUND Chronic cutaneous graft-vs-host disease (GVHD) is generally classified by whether lesions have a lichenoid or sclerodermatous morphology. Other unusual clinical forms have been reported that exhibit the features of dermatomyositis and lupus erythematosus. Within a large population of individuals who underwent allogeneic stem cell transplantation because of hematologic malignancy, a g...
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ژورنال
عنوان ژورنال: Current Pathobiology Reports
سال: 2018
ISSN: 2167-485X
DOI: 10.1007/s40139-018-0186-6